The University of Texas MD Anderson Cancer Center,
Houston, TX conducted a study on the effect of giving Juice Plus+ capsules and
Complete to ovarian cancer survivors. The study was published in the March 2012
issue of the
Gynecologic Oncology Journal.
This study demonstrated that adding Juice Plus+
capsules and the Juice Plus+ Complete
whole-food based shake mix helped ovarian cancer patients achieve a 10-a-day
regimen of fruit and vegetable consumption, with significant health benefits
A randomized parallel-group dietary study for
stages II–IV ovarian cancer survivors
Department of Gynecologic
Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer
Center, Houston, TX. Publishing in the March 2012 issue of theGynecologic
Few studies have examined the dietary habits of
ovarian cancer survivors. Therefore, we conducted a study to assess the
feasibility and impact of two dietary interventions for ovarian cancer
In this randomized, parallel-group study, 51 women
(mean age, 53 years) diagnosed with stages II–IV ovarian cancer were recruited
and randomly assigned to a low fat, high fiber (LFHF) diet or a modified
National Cancer Institute diet supplemented with a soy-based beverage (Juice
Plus+ Complete) and encapsulated fruit and vegetable juice concentrates (Juice
Plus+ Orchard and Garden Blends). Changes in clinical measures, serum carotenoid
and tocopherol levels, dietary intake, anthropometry, and health-related quality
of life (HRQOL) were assessed with paired t-tests.
The recruitment rate was 25%, and the retention
rate was 75% at 6 months. At baseline, 28% and 45% of women met guidelines for
intake of fiber and of fruits and vegetables, respectively. After 6 months,
total serum carotenoid levels and α- and β-carotene concentrations were
significantly increased in both groups (P < 0.01); however, β-carotene
concentrations were increased more in the Juice Plus+ group. Serum β-cryptoxanthin
levels, fiber intake (+ 5.2 g/day), and daily servings of juice
(+ 0.9 servings/day) and vegetables (+ 1.3 servings/day) were all significantly
increased in the LFHF group (allP < 0.05).
Serum levels of albumin, lutein and zeaxanthin, retinol, and retinyl palmitate
were significantly increased in the Juice Plus+ group (allP < 0.05).
No changes in cancer antigen-125, anthropometry, or HRQOL were observed.
Overall, this study supports the feasibility of
designing dietary interventions for stages II–IV ovarian cancer survivors and
provides preliminary evidence that a low fat high fiber diet and a diet
supplemented with encapsulated Juice Plus+ may increase phytonutrients in ovarian
Many ovarian cancer survivors
fail to meet current guidelines for dietary intake.
A low-fat diet supplemented with
Juice Plus+ can improve carotenoid
Juice Plus+ capsules and complete
may help bridge the gap between what is consumed and what is needed.